{"product_id":"biolegend-366903","title":"Biolegend, 366903, PE anti-human IgG Fc Recombinant Antibody, 25tests","description":"\u003cp\u003eIgG Fc is a homodimer composed of the constant region of the two heavy chains that form the IgG molecule. The Fc fragment mediates opsonization, antibody dependent cellular cytotoxicity (ADCC), and complement activation through binding to Fc receptors such as CD16, CD32, CD64, and the complement factor C1.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Anti-human IgG Fc antibody (clone QA19A42) may cross-react with bovine IgG. Anti-human IgG Fc antibody (clone M1310G05) does not exhibit this cross-reactivity.\u003cbr\u003e\nProduct Citations: Mulgaonkar A, et al. 2022. Clin Cancer Res. 28:4907. PubMed Fernandes LA, et al. 2022. Protein Sci. 31:e4355. PubMed\u003cbr\u003e\nRRID: AB_2876689 (BioLegend Cat. No. 366903) AB_2876689 (BioLegend Cat. No. 366904)\u003cbr\u003e\nStructure: Homodimer formed by the constant region of the IgG heavy chain\u003cbr\u003e\nLigand\/Receptor: CD16, CD32, CD64\u003cbr\u003e\nCell Type: B cells, Basophils, Dendritic cells, Macrophages, Mast cells, Neutrophils, NK cells, Platelets\u003cbr\u003e\nBiology Area: Adaptive Immunity, Cell Biology, Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: Fc Receptors\u003cbr\u003e\nAntigen References: Paul WE. 2003. Fundamental Immunology. Lippincott Williams \u0026amp; Wilkins. Philadelphia PA.\u003cbr\u003e\nGene ID: 3500\u003cbr\u003e\nUniProt: View information about IgG Fc on UniProt.org\u003cbr\u003e\nClone: QA19A42\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Immunoglobulin G\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866188665001,"sku":"366903","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-366903","provider":"Iright","version":"1.0","type":"link"}