{"product_id":"biolegend-372406","title":"Biolegend, 372406, APC anti-human HLA-B7 Antibody, 100tests","description":"\u003cp\u003eHLA-B belongs to the HLA class I heavy chain paralogues. HLA-B7 is a serotype of HLA-B and one of the common HLA types. MHC class I heavy chains associate with β2-microglobulin and are expressed on nearly all nucleated cells. MHC class I molecules are involved in the presentation of of antigens to CD8 + T cells and thereby play an important role in cell-mediated immune responses and immune surveillance.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Papain solubilized HLA antigen, B7.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Dellgren C, et al. 2015. PLoS One 10:e0135385. Brodsky F, et al. 1979. Immunol. Rev. 47:3. Rancan C, et al. 2015. PLoS Pathog. 11:e1004906. Levering W, et al. 2000. Cytometry 42:95.\u003cbr\u003e\nRRID: AB_2650775 (BioLegend Cat. No. 372405) AB_2650776 (BioLegend Cat. No. 372406)\u003cbr\u003e\nStructure: Ig superfamily.\u003cbr\u003e\nDistribution: Nearly all cells from HLA-B*07 individuals.\u003cbr\u003e\nFunction: Antigen peptide presentation.\u003cbr\u003e\nLigand\/Receptor: TCR, CD8.\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: MHC Antigens\u003cbr\u003e\nGene ID: 3106\u003cbr\u003e\nUniProt: View information about HLA-B7 on UniProt.org\u003cbr\u003e\nClone: BB7.1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: HLA-A7, HLA-B*07, HLA Class I histocompatibility antigen B alpha chain\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862900920489,"sku":"372406","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-372406","provider":"Iright","version":"1.0","type":"link"}