{"product_id":"biolegend-373903","title":"Biolegend, 373903, APC anti-human FcRL6 Antibody, 25tests","description":"\u003cp\u003eFcRL6, a member of Fc receptor-like family, does not bind Ig. It is expressed on cytotoxic NK and a subset of T cells (primarily CD8 + T cells).  Its expression level correlates with the differentiation state of these cells. This Type I transmembrane glycoprotein consists of three Ig-like domains on its extracellular and a consensus ITIM or non-canonical ITAM-like sequence on its cytoplasmic region. Patients with chronic lymphocytic leukemia show higher abundance of this receptor due to expansion of cytotoxic lymphocyte population.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: BW5147 transduced with HA-tagged FcRL6\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Schreeder DM, et al. 2008. Eur. J. Immunol. 38:3159. (FC)\u003cbr\u003e\nRRID: AB_2876702 (BioLegend Cat. No. 373903) AB_2876702 (BioLegend Cat. No. 373904)\u003cbr\u003e\nStructure: Type I transmembrane glycoprotein, Ig gene superfamily\u003cbr\u003e\nDistribution: NK, T subset\u003cbr\u003e\nCell Type: NK cells, T cells\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Fc Receptors\u003cbr\u003e\nAntigen References: 1. Davis RS. 2007. Annu. Rev. Immunol. 25:525. 2. Wilson TJ, et al. 2007. Blood 109:3786. 3. Schreeder DM, et al. 2008. 38:3159.\u003cbr\u003e\nGene ID: 343413\u003cbr\u003e\nUniProt: View information about FcRL6 on UniProt.org\u003cbr\u003e\nClone: 7B7\/FcRL6\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: FcRL6, Fc receptor like 6\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862484897961,"sku":"373903","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-373903","provider":"Iright","version":"1.0","type":"link"}