{"product_id":"biolegend-377119","title":"Biolegend, 377119, Purified anti-human EMR1 Antibody, 100μg","description":"\u003cp\u003eEGF-like module-containing mucin-like hormone receptor-like 1, also known as F4\/80, is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. Unlike its murine counterpart, which is widely used as a murine macrophage marker, the expression of human EMR1 is specific to eosinophils. Due to the restricted expression of EMR1, EMR1 is used as a therapeutic target for eosinophilic disorders.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Human ADGRE1\/EMR1 (a.a. 21-599)\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Clone W23100E does block the binding of clone QA19A76 on target cells.\u003cbr\u003e\nStructure: Seven transmembrane regions six EGF-like modules\u003cbr\u003e\nDistribution: Eosinophils\u003cbr\u003e\nAntigen References: Hamman J, et al. 2007. Eur J Immuno. 37:5797-2802 Akter R, et al. 2024. Int J Mol Sci. 25:4388.\u003cbr\u003e\nGene ID: 2015\u003cbr\u003e\nUniProt: View information about EMR1 on UniProt.org\u003cbr\u003e\nClone: W23100E\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Adhesion G protein-coupled receptor E1 (ADGRE1), EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, EMR1 hormone receptor, TM7LN3\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866438291625,"sku":"377119","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-377119","provider":"Iright","version":"1.0","type":"link"}