{"product_id":"biolegend-378903","title":"Biolegend, 378903, PE anti-human TSPAN8 Antibody, 25tests","description":"\u003cp\u003eTetraspanin 8 (TSPAN8) is a member of the transmembrane IV superfamily.  It is a cell surface protein with four hydrophobic domains. Tetraspanins are constitutive components of exosomes and are involved in adhesion, motility, matrix modulation and cell fusion. TSPAN8 mediates signal transduction events that regulate cell development, activation, growth, and motility. It is expressed in gastric, colon, rectal, and pancreatic carcinomas. \u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: huTSPAN8 transfectant\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nRRID: AB_2941553 (BioLegend Cat. No. 378903) AB_2941553 (BioLegend Cat. No. 378904)\u003cbr\u003e\nStructure: Multi-pass membrane protein\u003cbr\u003e\nDistribution: Cell membrane, lysosomes\u003cbr\u003e\nFunction: Tyrosine-based internalization, recruitment into endosomes\u003cbr\u003e\nInteraction: LIPR1, MEP1B, STX1-2, TIM23, S38A7\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nAntigen References: Szala S, et al. 1990. Proc Natl Acad Sci USA. 87:6833-7. Rana S, et al. 2011. Int J Biochem Cell Biol. 43:106-19. Nazarenko I, et al. 2010. Cancer Res. 70:1668-78. Berthier-Vergnes O, et al. 2011. Br J Cancer. 104:155-68.\u003cbr\u003e\nGene ID: 7103\u003cbr\u003e\nUniProt: View information about TSPAN8 on UniProt.org\u003cbr\u003e\nClone: S20010A\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Tetraspanin-8\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866264195241,"sku":"378903","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-378903","provider":"Iright","version":"1.0","type":"link"}