{"product_id":"biolegend-381902","title":"Biolegend, 381902, Purified anti-human CD166 Antibody, 100μg","description":"\u003cp\u003eCD166, also known as the CD6 ligand or the Activated Leukocyte Cell Adhesion Molecule (ALCAM), is a 100-105 kD transmembrane glycoprotein. It belongs to the Ig superfamily of proteins and expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, and neurons. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Recombinant human CD166 protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2936519 (BioLegend Cat. No. 381902)\u003cbr\u003e\nStructure: Type I transmembrane glycoprotein belonging to the Ig superfamily of proteins\u003cbr\u003e\nDistribution: CD166 is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, and neurons\u003cbr\u003e\nFunction: Play an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development\u003cbr\u003e\nLigand\/Receptor: CD6\u003cbr\u003e\nCell Type: Granulocytes, Monocytes, T cells\u003cbr\u003e\nBiology Area: Cell Adhesion, Immunology, Stem Cells\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: Aruffo A, et al. 1997. Immunol Today. 18:498-504. Bowen MA, et al. 1995. J Exp Med. 181:2213-20. Patel DD, et al. 1995. J Exp Med. 181:1563-8. Horst D, et al. 2009. Cancer Invest. 27:844-50.\u003cbr\u003e\nGene ID: 214\u003cbr\u003e\nUniProt: View information about CD166 on UniProt.org\u003cbr\u003e\nClone: A17193B\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CD6 ligand, Activated Leukocyte Cell Adhesion Molecule (ALCAM)\u003cbr\u003e\nIsotype: Mouse IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866056282281,"sku":"381902","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-381902","provider":"Iright","version":"1.0","type":"link"}