{"product_id":"biolegend-382603","title":"Biolegend, 382603, APC anti-human CD24 Antibody, 25tests","description":"\u003cp\u003eCD24 is a 35-45 kD glycosylphosphatidylinositol (GPI)-linked protein also known as heat stable antigen (HSA), BA-1, Ly-52, and nectadrin. It is expressed on the surface of B cells (but not plasma cells), granulocytes, follicular dendritic cells, and epithelial cells. CD24 may play a role in the regulation of B-cell proliferation and maturation. CD24 crosslinking induces a Ca 2+ flux in mature B cells. CD24 has been shown to interact with CD62P (P-selectin).\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Recombinant human CD24 protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication Notes: Clone W20001B can partially block binding of clone ML5 on target cells and is partially blocked by ML5.\u003cbr\u003e\nProduct Citations: Wei Y, et al. 2023. iScience. 108022:26. PubMed\u003cbr\u003e\nRRID: AB_2927986 (BioLegend Cat. No. 382603) AB_2927986 (BioLegend Cat. No. 382604)\u003cbr\u003e\nStructure: 35-45 kD glycosylphosphatidylinos GPI-linked protein\u003cbr\u003e\nDistribution: B lymphocytes, granulocytes, differentiating neurons, and epithelial cells\u003cbr\u003e\nFunction: Regulates B-cell proliferation and activation\u003cbr\u003e\nLigand\/Receptor: P-Selectin and Siglec-10\u003cbr\u003e\nCell Type: B cells, Epithelial cells, Granulocytes, Lymphocytes, Neural Stem Cells, T cells, Thymocytes\u003cbr\u003e\nBiology Area: Cancer Biomarkers, Cell Biology, Cell Motility\/Cytoskeleton\/Structure, Immuno-Oncology, Immunology, Neuroscience\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: Schlossman S, et al. 1995. Leukocyte Typing V. Oxford University Press. New York. Fang X, et al. 2010. Cellular and Molecular Immunology. 7:100-3.\u003cbr\u003e\nGene ID: 100133941\u003cbr\u003e\nUniProt: View information about CD24 on UniProt.org\u003cbr\u003e\nClone: W20001B\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Heat stable antigen (HSA), nectadrin, Ly-52\u003cbr\u003e\nIsotype: Mouse IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866417352873,"sku":"382603","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-382603","provider":"Iright","version":"1.0","type":"link"}