{"product_id":"biolegend-383902","title":"Biolegend, 383902, Purified anti-human EphA1 Antibody, 100μg","description":"\u003cp\u003eEphrin type-A receptor 1 (hEpha1), also known as EPH tyrosine kinase belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The protein consists of 976 a.a. with a molecular weight of 108 kD. The Eph subfamily represents the largest group of receptor protein tyrosine kinases and is divided into two major subclasses: ephrin-A and ephrin-B. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis and widely expressed in differentiated epithelial cells in the bone marrow, spleen, thymus, and testis.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2927851 (BioLegend Cat. No. 383902)\u003cbr\u003e\nStructure: The protein consists of 976 a.a. with a molecular weight of 108 kD.\u003cbr\u003e\nDistribution: Cytoplasmic and membranous expression in most tissues, including parathyroid gland\u003cbr\u003e\nFunction: Kinase, receptor, transferase, tyrosine-protein kinase. EphA1\/A2 and ephrin‐A1 are over‐expressed or downregulated in various types of cancer.\u003cbr\u003e\nInteraction: EphA1\/A2 and ephrin‐A1 are correlated with tumor malignancy and prognosis.\u003cbr\u003e\nLigand\/Receptor: Ephrin-A1\u003cbr\u003e\nCell Type: B cells, Endothelial cells, Epithelial cells, T cells, Thymocytes\u003cbr\u003e\nBiology Area: Cancer Biomarkers, Cell Adhesion, Immunology\u003cbr\u003e\nMolecular Family: Protein Kinases\/Phosphatase\u003cbr\u003e\nAntigen References: Katsuaki L and Yoshiro M. 2019. Cancer Sci. 110:841. Holen L, et al. 2010. J Leukoc Biol. 87:1059-68.\u003cbr\u003e\nGene ID: 2041\u003cbr\u003e\nUniProt: View information about EphA1 on UniProt.org\u003cbr\u003e\nClone: A20047D\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: EPH Receptor A1, Erythropoietin-Producing Hepatoma Receptor, Tyrosine-Protein Kinase Receptor EPH, Ephrin Type-A Receptor 1, EC 2.7.10.1, HEpha1, EPHT1, EPHT, EPH, Erythropoietin-Producing Hepatoma Amplified Sequence\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866069127337,"sku":"383902","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-383902","provider":"Iright","version":"1.0","type":"link"}