{"product_id":"biolegend-387002","title":"Biolegend, 387002, Purified anti-human CD213a2 (IL13Rα2) Antibody, 100μg","description":"\u003cp\u003eCD213a2, also known as IL13Rα2, is a type I transmembrane protein and member of the hematopoietin family. IL13Rα2 is the high affinity receptor for IL-13, but it possibly acts as a decoy receptor to antagonize IL-13Rα1\/IL-4Ra-mediated IL-13 biological functions. IL13Rα2 is expressed by fibroblasts, smooth muscle cells, keratinocytes and activated B cells. However, its presence on the cell surface is highly regulated. CD213a2 is also expressed in various types of cancer which makes it an attractive therapeutic target.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Recombinant human IL13Rα2, Cys22-Leu342\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2941571 (BioLegend Cat. No. 387002)\u003cbr\u003e\nStructure: Member of the hematopoietin family, type I transmembrane protein, contains 1 fibronectin type III domain\u003cbr\u003e\nDistribution: Fibroblasts, smooth muscle cells, keratinocytes, activated B cells\u003cbr\u003e\nFunction: Possible decoy receptor, antagonist of CD213a1, internalization of IL-13\u003cbr\u003e\nLigand\/Receptor: IL-13\u003cbr\u003e\nCell Type: B cells, Fibroblasts\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Transcription Factors\u003cbr\u003e\nMolecular Family: CD Molecules, Cytokine\/Chemokine Receptors\u003cbr\u003e\nAntigen References: Mitchell J, et al. 2010. Curr Opin Investig Drugs. 11:527-34. Strober W, et al. 2009. Curr Mol Med. 9:740-50. Tabata Y, et al. 2007. Curr Allergy Asthma Rep. 7:338-45.\u003cbr\u003e\nGene ID: 3598\u003cbr\u003e\nUniProt: View information about CD213a2 on UniProt.org\u003cbr\u003e\nClone: A21071B\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CD213a2, IL-13RA2, IL-13R, IL13BP, CT19\u003cbr\u003e\nIsotype: Mouse IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866074796201,"sku":"387002","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-387002","provider":"Iright","version":"1.0","type":"link"}