{"product_id":"biolegend-392302","title":"Biolegend, 392302, Purified anti-human CD282 (TLR2) Antibody, 100μg","description":"\u003cp\u003eToll-like receptors are type I transmembrane signaling receptors which are critical for the innate host defense to pathogens. Toll-like receptor 2 (TLR2), known as CD282, has been identified as a receptor that is central to the innate immune system's response to lipoproteins of Gram-negative bacteria and Gram-positive bacteria, as well as a receptor for peptidoglycan and lipoteichoic acid and other bacterial cell membrane products.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Full length human TLR2 transfected cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2721739 (BioLegend Cat. No. 392302)\u003cbr\u003e\nStructure: IL-1R superfamily, TLR family, type 1 transmebrane protein, 90kD\u003cbr\u003e\nDistribution: Monocytes, Granulocytes, endothelial and epithelial cells\u003cbr\u003e\nFunction: Activates innate host defense against bacterial pathogens\u003cbr\u003e\nLigand\/Receptor: Microbial lipoproteins, peptidoglycans, lipoteichoic acid\u003cbr\u003e\nCell Type: Endothelial cells, Epithelial cells, Granulocytes, Monocytes\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules, Toll Like Receptors\u003cbr\u003e\nAntigen References: 1. Lien E, et al. 1999. J. Biol. Chem. 274:33419. 2. Lien E, et al. 2001. J. Biol. Chem. 276:1873. 3. Sabroe I, et al. 2002. J. Immunol. 168:4701.\u003cbr\u003e\nGene ID: 7097\u003cbr\u003e\nUniProt: View information about CD282 on UniProt.org\u003cbr\u003e\nClone: W15145C\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: TLR2\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866299715753,"sku":"392302","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-392302","provider":"Iright","version":"1.0","type":"link"}