{"product_id":"biolegend-394212","title":"Biolegend, 394212, Brilliant Violet 421™ anti-human IL12RB2 Antibody, 100tests","description":"\u003cp\u003eIL12RB2 is a type I transmembrane protein that foms an heterodimer with IL12RB1 to produce the high affinity IL-12 receptor complex. IL12RB2 is expressed by activated T cells, TH1 cells, NK cells, B cells and plasma cells. Variants of this gene are associated with predisposition to various immune-related diseases.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Human IL12RB2 transfected cells.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450\/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd. Learn more about Brilliant Violet™. This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.\u003cbr\u003e\nExcitation Laser: Violet Laser (405 nm)\u003cbr\u003e\nRRID: AB_2922619 (BioLegend Cat. No. 394211) AB_2922619 (BioLegend Cat. No. 394212)\u003cbr\u003e\nStructure: Type I transmembrane protein, 3 isoforms, foms an heterodimer with IL12RB1\u003cbr\u003e\nDistribution: Activated T cells, TH1 cells, NK cells, B cells, plasma cells\u003cbr\u003e\nFunction: Role in TH1 differentiation\u003cbr\u003e\nLigand\/Receptor: IL-12\u003cbr\u003e\nCell Type: B cells, NK cells, Plasma cells, T cells, Th1\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Cytokine\/Chemokine Receptors\u003cbr\u003e\nAntigen References: LaMere SA, et al. 2017. J Immunol. 199:3158 Prigione I, et al. 2016. Immunobiology. 221:291 de Paus RA, et al. 2013. Mol Immunol. 56:380 Airoldi I, et al. 2008. Blood. 112:750\u003cbr\u003e\nGene ID: 3595\u003cbr\u003e\nUniProt: View information about IL12RB2 on UniProt.org\u003cbr\u003e\nClone: S16020B\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Interleukin-12 receptor subunit beta-2\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003cbr\u003e\nQ: What is the F\/P ratio range of our BV421™ format antibody reagents?\u003cbr\u003e\nA: It is lot-specific. On average it ranges between 2-4.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866227658921,"sku":"394212","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-394212","provider":"Iright","version":"1.0","type":"link"}