{"product_id":"biolegend-399305","title":"Biolegend, 399305, APC anti-human EOS Antibody, 25tests","description":"\u003cp\u003eEOS also known as IKZF4 is an IKAROS Family Member expressed in lymphocytes, specifically in Tregs. It plays an important role in the inhibitory function of Tregs. It may be involved in the development of the central and peripheral nervous systems as well as lymphoid development.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Human EOS recombinant protein (271-520a.a)\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication Notes: Clones W16032A and W16032B cross-block each other and likely recognize different epitopes.\u003cbr\u003e\nRRID: AB_2876724 (BioLegend Cat. No. 399305) AB_2876724 (BioLegend Cat. No. 399306)\u003cbr\u003e\nStructure: IKAROS Family Member\u003cbr\u003e\nDistribution: Lymphocytes, specifically in Tregs\u003cbr\u003e\nFunction: Essential for inhibitory function of Tregs\u003cbr\u003e\nInteraction: Binds to 5'GGGAATRCC-3' Ikaros-binding sequence\u003cbr\u003e\nAntigen References: Honma Y, et al. 1999. FEBS Lett. 447(1):76-80. Perdomo J, et al. 2000. J. Biol chem 275(49):38347-54. Westman BJ, et al. 2004. Biochemistry. 43(42):13318-27. Pan F, et al. 2009. Science. 325(5944):1142-6.\u003cbr\u003e\nGene ID: 64375\u003cbr\u003e\nUniProt: View information about EOS on UniProt.org\u003cbr\u003e\nClone: W16032A\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Ikaros family zinc finger protein 4 (IKZF4), ZMFN1A4, KIAA1782\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866302173353,"sku":"399305","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-399305","provider":"Iright","version":"1.0","type":"link"}