{"product_id":"biolegend-449904","title":"Biolegend, 449904, ELISA MAX™ Deluxe Set Human RAGE ELISA Kit, 5plates","description":"\u003cp\u003eReceptor for advanced glycation end products is a multi-ligand receptor that belongs to the immunoglobulin superfamily of cell surface molecules. It can be found in adult lung and skin tissue but low levels are found in other tissue types such as endothelia, cardio myocytes, neutrophils, macrophages, lymphocytes, dendritic cells, and the central nervous system. Due to the multi-ligand nature of RAGE, the receptor is involved in activation of many cell signal pathways such as ERK1\/2, p38, SHPK\/JNK MAP Kinases, rho GTPases, phosphoinositol-3-kinase (PI3K), and JAK\/STAT. It has been found to be involved in pathogenesis and complications that are age related such as diabetes and Alzheimer’s, as well as cellular processes such as inflammation, apoptosis, autophagy, and proliferation.\u003cbr\u003e\n5plates\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nApplication: ELISA\u003cbr\u003e\nSensitivity: 41.28 ± 39.7 pg\/mL\u003cbr\u003e\nStandard Range: 78.1 - 5000 pg\/mL\u003cbr\u003e\nCell Type: Dendritic cells, Endothelial cells, Lymphocytes, Macrophages, Neutrophils\u003cbr\u003e\nBiology Area: Cell Proliferation and Viability, COVID-19, Signal Transduction\u003cbr\u003e\nMolecular Family: Soluble Receptors\u003cbr\u003e\nGene ID: NA\u003cbr\u003e\nUniProt: View information about RAGE on UniProt.org\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Advanced glycosylation end product-specific receptor\u003cbr\u003e\nQ: Do the ELISA MAX™ Deluxe Sets come with plates?\u003cbr\u003e\nA: No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46864267313321,"sku":"449904","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-449904","provider":"Iright","version":"1.0","type":"link"}