{"product_id":"biolegend-504702","title":"Biolegend, 504702, Purified anti-mouse IL-9 Antibody, 500μg","description":"\u003cp\u003eIL-9 is a potent, T cell-derived, T cell growth factor which can also enhance mast cell activity and IL-3- or IL-4- dependent proliferation of bone marrow-derived mast cells. IL-9 synergizes with erythropoietin to promote erythroid colony formation. IL-9 induces high affinity IgE receptor expression and granzyme A and B in murine T helper clones. The D8402E8 antibody reacts with mouse IL-9.\u003cbr\u003e\n500μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Baculovirus-expressed, recombinant mouse IL-9\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: ELISA Capture\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 1-4 µg\/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-9 recombinant protein ranging from 4000 to 30 pg\/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: ELISA Capture1,2: The purified D8402E8 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated D9302C12 antibody (Cat. No. 504804) as the detecting antibody.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Abrams, J. 1995. Curr. Prot. Immunol. John Wiley and Sons, New York. Unit 6.20. Renauld, J., et al. 1995. J. Leuk. Biol. 57:353. Gounni, A.S.,et al.2004. J. Immunol.173:2771.J.Immunol\u003cbr\u003e\nProduct Citations: Gounni A, et al. 2004. J Immunol. 173:2771. PubMed\u003cbr\u003e\nRRID: AB_315344 (BioLegend Cat. No. 504702)\u003cbr\u003e\nStructure: Cytokine; 30-40 kD (Mammalian)\u003cbr\u003e\nBioactivity: Potentiates production of IgG, IgM, and IgE by IL-4-induced B lymphocytes; regulates granzyme family proteases; enhances proliferation of bone marrow mast cells with IL-3; production of IL-6 by mast cells\u003cbr\u003e\nCell Sources: IL-2 activated TH2 lymphocytes\u003cbr\u003e\nCell Targets: T lymphocytes, erythroid precursors\u003cbr\u003e\nReceptors: IL-9R\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Cytokines\/Chemokines\u003cbr\u003e\nAntigen References: 1. Fitzgerald, K., et al. Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Quesniaux, V. 1992. Research Immunology 143:385. 3. Renauld, J., et al. 1993. Adv. Immunol. 54:79. 4. Yang, Y. 1992. Leuk. Lymphoma 8:441.\u003cbr\u003e\nRegulation: Upregulated by IL-1 after TCR activation, TNF-α; downregulated by antibodies to IL-2\u003cbr\u003e\nGene ID: 16198\u003cbr\u003e\nUniProt: View information about IL-9 on UniProt.org\u003cbr\u003e\nClone: D8402E8\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Interleukin-9, P40, Mast cell growth factor (MCGF), Megakaryoblast growth factor, T cell growth factor-3 (TCGF-3)\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46863004958889,"sku":"504702","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-504702","provider":"Iright","version":"1.0","type":"link"}