{"product_id":"biolegend-515506","title":"Biolegend, 515506, Alexa Fluor® 647 anti-human RANTES (CCL5) Antibody, 100tests","description":"\u003cp\u003eRANTES (CCL5) is a member of the CC chemokine family. Its mature form consists of 68 amino acid residues. RANTES is a strong chemotractant for monocytes, NK cells, T cells, and eosinphils. RANTES may have important role in mediating immune and inflammatory responses.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: Rhesus\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: ICFC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm \/ 635nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Krensky AM, et al. 1997. Methods Enzymol. 287:162.\u003cbr\u003e\nProduct Citations: Tian L, et al. 2022. Nat Cancer. 3:1318. PubMed Sang M, et al. 2014. Antiviral Res. 112:103. PubMed\u003cbr\u003e\nRRID: AB_1877140 (BioLegend Cat. No. 515505) AB_2071300 (BioLegend Cat. No. 515506)\u003cbr\u003e\nStructure: Human RANTES cDNA is a member of the C-C chemokine family with a MW of around 8 kD. Human and mouse RANTES have 85% homology.\u003cbr\u003e\nDistribution: Reported to be produced by T cells, platelets, synovial fibroblasts, and some tumor cells.\u003cbr\u003e\nFunction: Able to chemoattract monocytes, NK cells, eosinophils, and T cells.\u003cbr\u003e\nInteraction: Monocytes, NK cells, T cells, and eosinophils.\u003cbr\u003e\nCell Type: Fibroblasts, Platelets, T cells\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience\u003cbr\u003e\nMolecular Family: Cytokines\/Chemokines\u003cbr\u003e\nAntigen References: 1. Von Luettichau. et al. 1996. Cytokine 8:89. 2. Schall TJ. 1991. Cytokine 3:165.\u003cbr\u003e\nGene ID: 6352\u003cbr\u003e\nUniProt: View information about RANTES on UniProt.org\u003cbr\u003e\nClone: VL1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CCL5, C-C motif chemokine 5, Small-inducible cytokine A5, T-cell-specific protein RANTES, SIS-delta, T cell-specific protein P228, TCP228, Eosinophil-chemotactic cytokine, EoCP\u003cbr\u003e\nIsotype: Mouse IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46864084107433,"sku":"515506","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-515506","provider":"Iright","version":"1.0","type":"link"}