{"product_id":"biolegend-519507","title":"Biolegend, 519507, PE\/Cyanine7 anti-human CXCL10 (IP-10) Antibody, 25tests","description":"\u003cp\u003eCXCL10, also known as IP-10, is a 8.7 kD chemokine. It belongs to the CXC chemokine family. It is expressed by monocytes, fibroblasts, and endothelial cells in response to IFNγ. It can interact with CXCR3 and plays an important role in immune cell trafficking, particularly of T cells, dendritic cells, and NK cells. In addition, it alters expression of adhesion molecules.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: Rhesus\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE\/Cyanine7 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: ICFC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nRRID: AB_2904432 (BioLegend Cat. No. 519507) AB_2904432 (BioLegend Cat. No. 519508)\u003cbr\u003e\nStructure: CXC chemokine family, 8.7 kD\u003cbr\u003e\nDistribution: Monocytes, endothelial cells, and fibroblasts\u003cbr\u003e\nFunction: Interacts with CXCR3 and serves as a chemoattractant for T cells, dendritic cells, monocytes\/macrophages, and NK cells\u003cbr\u003e\nLigand\/Receptor: CXCR3\u003cbr\u003e\nCell Type: B cells, Dendritic cells, Endothelial cells, Fibroblasts, Monocytes\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience\u003cbr\u003e\nMolecular Family: Cytokines\/Chemokines\u003cbr\u003e\nAntigen References: 1. Luster AD, et al. 1987. Proc. Natl. Acad. Sci. USA 84:2868. 2. Kaplan G, et al. 1987. J. Exp. Med. 166:1098. 3. Sarris AH, et al. 1993. J. Exp. Med. 178:1127.\u003cbr\u003e\nGene ID: 3627\u003cbr\u003e\nUniProt: View information about CXCL10 on UniProt.org\u003cbr\u003e\nClone: J034D6\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Interferon gamma induced protein-10 (IP-10)\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866106319017,"sku":"519507","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-519507","provider":"Iright","version":"1.0","type":"link"}