{"product_id":"biolegend-613952","title":"Biolegend, 613952, Purified anti-FABP5 Antibody, 100μg","description":"\u003cp\u003eFatty Acid Binding Protein 5 (FABP5) is a protein that plays an important role in the regulation of cellular fatty acid metabolism. Initially discovered in epidermal cells, FABP5 binds long-chain fatty acids and other related hydrophobic molecules to facilitate their uptake into the cell. Utilizing this transport function, FABP5 plays an important role in regulating fatty acid metabolism and energy homeostasis. Additionally, FABP5 is capable of transporting lipid-based signaling molecules such as endocannabinoids, functioning in diverse pathways such as glucose homeostasis, retinoic acid signaling, and the inflammatory response.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human, Mouse, Rat\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Recombinant full-length human FABP5\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: WB - Quality testedIHC-P - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.25 - 1.0 µg\/mL. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 0.25 - 1.0 µg\/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: For IHC-P, titration to concentrations below 0.25 µg\/mL may improve results.\u003cbr\u003e\nRRID: AB_2941614 (BioLegend Cat. No. 613951) AB_2941614 (BioLegend Cat. No. 613952)\u003cbr\u003e\nStructure: FABP5 is a 135 amino-acid protein with a predicted molecular weight of 15.1 kD.\u003cbr\u003e\nDistribution: Plasma membrane, keratinocytes and epithelial cells\u003cbr\u003e\nFunction: Transporter\u003cbr\u003e\nLigand\/Receptor: Long-chain fatty acids and related lipids\u003cbr\u003e\nCell Type: Epithelial cells\u003cbr\u003e\nBiology Area: Neuroscience, Signal Transduction\u003cbr\u003e\nMolecular Family: Neurotransmitter Receptor Trafficking\/Endocytosis\u003cbr\u003e\nAntigen References: Hotamisligil GS and Bernlohr DA. 2015. Nat Rev Endocrinol. 11:592-605. Nowowiejska J, et al. 2022. Metabolites. 12:833. Xu B, et al. 2022. Front Cell Dev Biol. 10:857919.\u003cbr\u003e\nGene ID: 2171\u003cbr\u003e\nUniProt: View information about FABP5 on UniProt.org\u003cbr\u003e\nClone: CPTC-FABP5-1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Fatty acid-binding protein 5 (FABP5), Epidermal-type fatty acid-binding protein (E-FABP), Psoriasis-associated fatty acid-binding protein homolog (PA-FABP)\u003cbr\u003e\nIsotype: Mouse IgG1\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862994112681,"sku":"613952","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-613952","provider":"Iright","version":"1.0","type":"link"}