{"product_id":"biolegend-635501","title":"Biolegend, 635501, Purified anti-TCP-1β Antibody, 25μg","description":"\u003cp\u003eTCP-1β (Chaperonin containing T complex polypeptide 1, subunit 2) belongs to the TCP-1 chaperonin family, predicted molecular weight 57 kD. Chaperonin-containing TCP-1 is a large multisubunit complex of 800-900 kD, a protein complex considered to be the cytosolic homologue of mitochondrial HSP60. TCP-1β has been shown to interact with β-actin, 14-3-3, SUMO4, TCP-1α, β-Tubulin, α-Tubulin and CCT8. In vitro, TCP-1βmediates the ATP-dependent folding of tubulin, actin, and α-transducin. This protein is also essential for cyclin E maturation and accumulation.Clone F39P7F11has been shown to be useful for western blotting and immunohistochemistry of human, mouse, rat and Frog TCP-1β.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Human, Mouse, Rat, Frog\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Ovalbumin-conjugated synthetic Peptide RKRVPDHHPC\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: Upon receipt, store undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: WB - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 5-10 µg per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Coghlin C, et al. 2006. J Pathol. 210:351. PubMed\u003cbr\u003e\nProduct Citations: Coghlin C, et al. 2006. J Pathol. 210:351. PubMed Arines FM, et al. 2021. J Cell Biol. 220:. PubMed\u003cbr\u003e\nRRID: AB_2275598 (BioLegend Cat. No. 635502)\u003cbr\u003e\nStructure: Belongs to the TCP-1 chaperonin family, predicted molecular weight 57 kD.\u003cbr\u003e\nDistribution: Cytoplasm\u003cbr\u003e\nFunction: In vitro, TCP-1β mediates the ATP-dependent folding of tubulin, actin, and α-transducin. This protein is also essential for cyclin E maturation and accumulation.\u003cbr\u003e\nInteraction: β-actin, 14-3-3γ, SUMO4, TCP-1α, β-Tubulin, α-tubulin, CCT8\u003cbr\u003e\nBiology Area: Cell Biology, Cell Motility\/Cytoskeleton\/Structure\u003cbr\u003e\nAntigen References: 1. Yaffe MB, et al. 1992. Nature 358:245\u003cbr\u003e\nGene ID: 21454\u003cbr\u003e\nUniProt: View information about TCP-1 beta on UniProt.org\u003cbr\u003e\nClone: F39P7F11\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CCT beta, CCTB, T-complex protein 1 subunit beta, TCP1 beta\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46863988031657,"sku":"635501","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-635501","provider":"Iright","version":"1.0","type":"link"}