{"product_id":"biolegend-828301","title":"Biolegend, 828301, Purified anti-p120 Catenin Antibody (Previously Covance catalog# MMS-5040), 100microl","description":"\u003cp\u003ep120\/Catenin delta-1 (CTNND1) is a membrane protein that binds to cadherins and participates in signal transduction.  It is the prototypic member of a growing subfamily of Armadillo-domain proteins found at cell-cell junctions and in nuclei.  Known to bind specifically to presenilin 1, it regulates the maintenance of dendrites and dendritic spines in mature cortex.\u003cbr\u003e\n100microl\u003cbr\u003e\nVerified Reactivity: Human, Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: This monoclonal antibody was raised against tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60\/c-src 527F and 2A\/527F.\u003cbr\u003e\nFormulation: Phosphate-buffered solution.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 1 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.\u003cbr\u003e\nApplication: WB - Quality testedIP - Reported in the literature, not verified in house\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5 - 10 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Kanner S., et al. Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells. Mol Cell Bio, 11(2): 713-720, February 1991. Kanner S., et al. Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases. Proc Natl Acad Sci U.S.A., 87(9): 3328-3332, May 1990. Staddon JM, et al. 1995. J. Cell. Biol. 130:369. (WB, IP) Kim L and Wong TW, et al. 1995. Mol. Cell. Biol. 15:4553. (WB, IP)\u003cbr\u003e\nProduct Citations: Alharatani R, et al. 2020. Hum Mol Genet. 29:1900. PubMed\u003cbr\u003e\nRRID: AB_2564919 (BioLegend Cat. No. 828301)\u003cbr\u003e\nStructure: Expected MW: 115 kD\u003cbr\u003e\nBiology Area: Cell Biology, Neuroscience, Synaptic Biology\u003cbr\u003e\nMolecular Family: Adhesion Molecules\u003cbr\u003e\nGene ID: 1500\u003cbr\u003e\nUniProt: View information about p120 Catenin on UniProt.org\u003cbr\u003e\nClone: 2B12\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CAS, p120, CTNND, P120CAS, P120CTN, p120(CAS), p120(CTN), catenin delta-1\u003cbr\u003e\nPreviously: Covance Catalog# MMS-5040\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866540331177,"sku":"828301","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-828301","provider":"Iright","version":"1.0","type":"link"}