{"product_id":"biolegend-846902","title":"Biolegend, 846902, Purified anti-Thyroglobulin Antibody, 100μg","description":"\u003cp\u003eThyroglobulin (Tg) is a dimeric glycoprotein that is predominantly produced by follicular cells of the thyroid. This protein is secreted from the endoplasmic reticulum to the follicular lumen. Tg acts as a substrate for the synthesis of thyroxine (T4) and triiodothyronine (T3) as well as storage of inactive forms of thyroid hormone and iodine .\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Recombinant human thyroglobulin protein.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: IHC-P - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 5.0 μg\/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2629663 (BioLegend Cat. No. 846902)\u003cbr\u003e\nStructure: Thyroglobulin is a 2768 amino acid protein with a molecular mass of 305 kD.\u003cbr\u003e\nDistribution: Tissue distribution: thyroid. Cellular distribution: extracellular, endoplasmic reticulum and plasma membrane.\u003cbr\u003e\nFunction: Thyroglobulin is the precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3).\u003cbr\u003e\nInteraction: HSPA5\u003cbr\u003e\nBiology Area: Cell Biology, Neuroscience\u003cbr\u003e\nMolecular Family: Hormones\u003cbr\u003e\nAntigen References: 1. Ma ZF, Skeaff SA. 2014. Thyroid 24(8):1195-209. PubMed 2. Sellitti DF, Suzuki K. 2014. Thyroid 24(4):625. PubMed 3. Bellet D, et al. 1983. J. Clin. Endocrinol. Metab. 56:530. PubMed\u003cbr\u003e\nGene ID: 7038\u003cbr\u003e\nUniProt: View information about Thyroglobulin on UniProt.org\u003cbr\u003e\nClone: BSB-49\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Tg\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862917304489,"sku":"846902","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-846902","provider":"Iright","version":"1.0","type":"link"}