{"product_id":"biolegend-853802","title":"Biolegend, 853802, Purified anti-Chil3 Antibody, 100μg","description":"\u003cp\u003eChitinases are hydrolytic enzymes that break down glycosidic bonds in chitin. Chitinase-like protein 3 (Chil3) hydrolyzes terminal non-reducing N-acetyl-D-hexosamine residues into N-acetyl-beta-D-hexosaminides. This protein is particular enriched in the spleen.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Recombinant mouse Chil3\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: WB - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2750120 (BioLegend Cat. No. 853801) AB_2750121 (BioLegend Cat. No. 853802)\u003cbr\u003e\nStructure: Chil3 is a 398 amino acid protein with a molecular weight mass of ~45 kD.\u003cbr\u003e\nDistribution: Tissue distribution: Spleen, macrophages, and bone marrow-derived neutrophils. Cellular distribution: Nucleus, endoplasmic reticulum, and secreted.\u003cbr\u003e\nFunction: Chil3 plays a role in hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.\u003cbr\u003e\nInteraction: Chil3 binds to chitin, lectin, and heparin.\u003cbr\u003e\nCell Type: Macrophages, Neutrophils\u003cbr\u003e\nBiology Area: Cell Biology, Neuroinflammation, Neuroscience, Neuroscience Cell Markers\u003cbr\u003e\nMolecular Family: Enzymes and Regulators\u003cbr\u003e\nAntigen References: Mesci P, et al. 2015. Brain. 138:53-68 Wu F, et al. 2016. Parasitol Res. 115:3737 Al-Rubaie A, et al. 2018. Respir Res. 19:114\u003cbr\u003e\nGene ID: 12655\u003cbr\u003e\nUniProt: View information about Chil3 on UniProt.org\u003cbr\u003e\nClone: A17046B\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Chitinase-like protein 3, Chil3, Beta-N-acetylhexosaminidase Ym1, Ym1, ECF-L, Eosinophil chemotactic cytokine\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46864405790889,"sku":"853802","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-853802","provider":"Iright","version":"1.0","type":"link"}