{"product_id":"biolegend-865802","title":"Biolegend, 865802, Purified anti-Phostensin Antibody, 100μg","description":"\u003cp\u003ePhostensin is a protein that targets protein phosphatase 1 (PP1) to F-actin cytoskeleton. The phostensin\/PP1 complex is involved in actin cytoskeleton remodeling. Diseases associated with phostensin include deafness and  autosomal recessive 79.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Purified recombinant human phostensin protein fragments expressed in E.coli\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: WB - Quality testedIHC-P - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2.0 - 5.0 µg per ml. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 2.0 - 5.0 µg\/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2810781 (BioLegend Cat. No. 865801) AB_2810782 (BioLegend Cat. No. 865802)\u003cbr\u003e\nStructure: Phostensin is a 613 amino acid protein with an observed molecular mass of ~100 kD.\u003cbr\u003e\nDistribution: Tissue Distribution: Brain, spleen, lymph node, and leukocytes Cellular Distribution: Cytoskeleton, nucleus, and cytosol\u003cbr\u003e\nFunction: Phostensin is involved in the regulation of protein phosphase-1 activity by targeting it to the F-actin cytoskeleton.\u003cbr\u003e\nInteraction: Protein Phosphatase-1, F-actin\u003cbr\u003e\nCell Type: Lymphocytes, Neurons\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Neurodegeneration, Neuroscience, Signal Transduction\u003cbr\u003e\nMolecular Family: Cytoskeletal Proteins, Enzymes and Regulators, Phospho-Proteins, Protein Modifiers\u003cbr\u003e\nAntigen References: Matsubara T, et al. 2018. Mol Cell Biol. 38(4). pii: e00425. Lin YS, et al. 2011. J Histochem Cytochem. 59(8):741.\u003cbr\u003e\nGene ID: 170954\u003cbr\u003e\nUniProt: View information about Phostensin on UniProt.org\u003cbr\u003e\nClone: 4B12-E11-D9\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Protein Phosphatase 1 Regulatory Subunit 18, Protein Phosphatase 1 F-Actin Cytoskeleton Targeting Subunit, KIAA1949\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862410580137,"sku":"865802","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-865802","provider":"Iright","version":"1.0","type":"link"}