{"product_id":"biolegend-919001","title":"Biolegend, 919001, Purified anti-HIV TAT Antibody (Previously Covance catalog# MMS-116P), 250microl","description":"\u003cp\u003eThe HIV-1 TAT (transactivator of transcription) gene codes for a 14 kD protein and is vital for HIV-1 transcription. After infection, TAT is one of the first proteins expressed after HIV has taken over the host’s machinery. TAT is a RNA binding protein that recognizes the TAR (Transactivator Response Element) sequence found in the HIV-1 RNA molecule. It is also needed for the recruitment of the host positive transcription elongation factor b (p-TEFb). In neuron cells, TAT has been linked to progressive neuronal deregulation, HIV-Associated Neurocognitive Disorders and accelerating brain aging.\u003cbr\u003e\n250microl\u003cbr\u003e\nVerified Reactivity: HIV\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: This antibody was generated against full-length HIV TAT protein.\u003cbr\u003e\nFormulation: Phosphate-buffered solution + 0.03% Thimerosal.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 1 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.\u003cbr\u003e\nApplication: WB\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. The optimal working dilution should be determined for each specific assay condition. • WB: 1:1,000*\u003cbr\u003e\nApplication Notes: This antibody is effective in immunoblotting (WB). *Predicted MW = 11 kD The epitope is contained in the first 37 amino acids of the protein.\u003cbr\u003e\nProduct Citations: Hategan A, et al. 2017. Nat Struct Mol Biol. 10.1038\/nsmb.3379. PubMed\u003cbr\u003e\nRRID: AB_2565207 (BioLegend Cat. No. 919001)\u003cbr\u003e\nBiology Area: Bacterial proteins and Toxins, Cell Biology\u003cbr\u003e\nGene ID: 155871\u003cbr\u003e\nUniProt: View information about HIV TAT on UniProt.org\u003cbr\u003e\nClone: AC11.AE12\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: HIV TAT\u003cbr\u003e\nPreviously: Covance Catalog# MMS-116P\u003cbr\u003e\nIsotype: Mouse IgG1\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862528708777,"sku":"919001","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-919001","provider":"Iright","version":"1.0","type":"link"}