{"product_id":"cst-12778t","title":"CST,  12778T, NCK1 (5B7) Mouse Monoclonal Antibody","description":"Monoclonal Antibody for studying NCK1. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, NCK1 (5B7) Mouse Monoclonal Antibody (CST #12778) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nNCK1 (5B7) Mouse Monoclonal Antibody recognizes endogenous levels of total NCK1 protein.\nSpecies Reactivity: Human, Mouse, Rat, Hamster, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with recombinant protein corresponding to a fragment of human NCK1 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nNCK adapter protein 1 (NCK1), also known as NCK or NCKα, is a broadly expressed oncogenic adapter protein consisting of three SH3 domains and one SH2 domain (1-3). NCK1 becomes phosphorylated upon activation of variety of cell surface receptors and is involved in actin cytoskeletal organization induced by many stimuli (4-6). NCK2, also known as NCKβ, a homolog of NCK1, has an overlapping expression pattern and redundant functions with NCK1 (7).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCytoplasmic protein NCK1; melanoma NCK protein; MGC12668; NCK; NCK adaptor protein 1; NCK tyrosine kinase; Nck-1; NCK1; NCKalpha; non-catalytic region of tyrosine kinase; SH2\/SH3 adaptor protein NCK-alpha\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Hm Mk\nSENSITIVITY: Endogenous\nMW (kDa): 47\nSource\/Isotype: Mouse IgG1","brand":"CST","offers":[{"title":"Default Title","offer_id":46797580337321,"sku":"12778T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/cst-12778t","provider":"Iright","version":"1.0","type":"link"}