{"product_id":"proteintech-10691-1-ap","title":"Proteintech, 10691-1-AP, E2F6 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe E2F6 (10691-1-AP) by Proteintech is a Polyclonal antibody targeting E2F6 in WB, ELISA applications with reactivity to human samples\n10691-1-AP targets E2F6 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, HepG2 cells,  HuH-7 cells,  K-562 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nE2F6 is a member of the E2F family of transcription factors, which play important roles in cell cycle regulation and gene expression. E2F6 is highly expressed in many types of cancer and is associated with poor prognosis. It is involved in the regulation of cell proliferation and can promote tumor growth. E2F6 knockdown significantly reduces the proliferative ability of glioma cells (PMID: 38071912). Additionally, E2F6 is related to immune activation markers, tumor immune cell infiltration, and immune regulators, making it a potential biomarker for predicting the response to cancer immunotherapy.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag1029 Product name: Recombinant human E2F6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-281 aa of BC008348 Sequence: MSQQRPARKLPSLLLDPTEETVRRRCRDPINVEGLLPSKIRINLEDNVQYVSMRKALKVKRPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKKSKNHIRWIGSDLSNFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENERLAYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLCEVEQGQTSNKRSEGVGTSSSESTHPEGPEEEENPQQSEELLEVSN Predict reactive species\nFull Name: E2F transcription factor 6\nCalculated Molecular Weight: 32 kDa\nObserved Molecular Weight: 37 kDa\nGenBank Accession Number: BC008348\nGene Symbol: E2F6\nGene ID (NCBI): 1876\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O75461\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887402406057,"sku":"10691-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-10691-1-ap","provider":"Iright","version":"1.0","type":"link"}