{"product_id":"proteintech-10930-1-ap","title":"Proteintech, 10930-1-AP, ARPC4 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ARPC4 (10930-1-AP) by Proteintech is a Polyclonal antibody targeting ARPC4 in WB, IHC, ELISA applications with reactivity to human,  mouse,   rat samples\n10930-1-AP targets ARPC4 in WB, IHC, IF, IP, ELISA applications and shows reactivity with human,  mouse,   rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue, mouse small intestine tissue,  rat lymph tissue,  4T1 cells,  human placenta tissue,  human brain tissue,  mouse cerebellum tissue,  MCF-7 cells\nPositive IHC detected in: human cervical cancer tissue, human testis tissue,  human lung cancer tissue,  human urothelial carcinoma tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe ARP2\/3 complex consists of seven subunits: two actin-related proteins (ARP2 and ARP3) and five ARP2\/3 complex polypeptides (ARPC1B and ARPC2-5). ARPC4 is a core subunit of the actin-related protein (ARP2\/3) complex, which catalyzes the formation of F-actin networks. ARPC4 is essential for the structural integrity of the ARP2\/3 complex function. Mutations in ARPC4 cause Developmental delay, language impairment, and ocular abnormalities (DEVLO)(PMID: 35047857).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse, bovine\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag1366 Product name: Recombinant human ARPC4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-167 aa of BC012596 Sequence: TATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFTMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF Predict reactive species\nFull Name: actin related protein 2\/3 complex, subunit 4, 20kDa\nCalculated Molecular Weight: 20 kDa\nObserved Molecular Weight: 19-25 kDa\nGenBank Accession Number: BC012596\nGene Symbol: ARPC4\nGene ID (NCBI): 10093\nRRID: AB_2059951\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P59998\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868977123497,"sku":"10930-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-10930-1-ap","provider":"Iright","version":"1.0","type":"link"}