{"product_id":"proteintech-11230-1-ap","title":"Proteintech, 11230-1-AP, Casein Kinase 1 Epsilon Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe Casein Kinase 1 Epsilon (11230-1-AP) by Proteintech is a Polyclonal antibody targeting Casein Kinase 1 Epsilon in WB, IHC, ELISA applications with reactivity to human, mouse, rat samples\n11230-1-AP targets Casein Kinase 1 Epsilon in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A431 cells,  mouse brain tissue\nPositive IHC detected in: human breast cancer tissue, human heart tissue,  human kidney tissue,  human testis tissue,  human ovary tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:200-1:1000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCSNK1E(Casein kinase I isoform epsilon) is also named as CKIe, CKI-epsilon and belongs to the casein kinase I subfamily. It plays a significant role in delaying the negative feedback signal within the transcription-translation-based autoregulatory loop that composes the core of the circadian mechanism and makes an ideal target for pharmaceutical compounds influencing circadian rhythms, sleep, and jet lag, as well as other physiologic and metabolic processes under circadian regulation(PMID:10775102). It can be autophosphorylated(PMID:19690332).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag1742 Product name: Recombinant human CSNK1E protein Source: e coli. -derived, PKG Tag: GST Domain: 116-416 aa of BC006490 Sequence: IEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAGNTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK Predict reactive species\nFull Name: casein kinase 1, epsilon\nCalculated Molecular Weight: 47 kDa\nObserved Molecular Weight: 46-52 kDa\nGenBank Accession Number: BC006490\nGene Symbol: CK1 epsilon\nGene ID (NCBI): 1454\nRRID: AB_2084501\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P49674\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869449146537,"sku":"11230-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-11230-1-ap","provider":"Iright","version":"1.0","type":"link"}