{"product_id":"proteintech-11391-1-ap","title":"Proteintech, 11391-1-AP, PROCR\/EPCR\/CD201 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PROCR\/EPCR\/CD201 (11391-1-AP) by Proteintech is a Polyclonal antibody targeting PROCR\/EPCR\/CD201 in WB, IHC, ELISA applications with reactivity to human samples\n11391-1-AP targets PROCR\/EPCR\/CD201 in WB, IHC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: human spleen tissue\nPositive IHC detected in: human pancreas cancer tissue,  human lung cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nProtein C receptor (PROCR), also known as activated protein C receptor (APC receptor), EPCR, or CD201, is a transmembrane glycoprotein. EPCR promotes the activation of protein C, which has anticoagulant and cytoprotective effects. EPCR facilitates the activation of protein C by the thrombin-thrombomodulin complex but also facilitates APC-mediated cytoprotective effects on cells that involve the activation of protease-activated receptors (PAR) 1 and 3(PMID: 27207424).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag1937 Product name: Recombinant human PROCR protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-238 aa of BC014451 Sequence: MLTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTSLVLGVLVGGFIIAGVAVGIFLCTGGRRC Predict reactive species\nFull Name: protein C receptor, endothelial (EPCR)\nCalculated Molecular Weight: 238 aa, 27 kDa\nObserved Molecular Weight: 49 kDa\nGenBank Accession Number: BC014451\nGene Symbol: PROCR\nGene ID (NCBI): 10544\nRRID: AB_2268938\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9UNN8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869737046185,"sku":"11391-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-11391-1-ap","provider":"Iright","version":"1.0","type":"link"}