{"product_id":"proteintech-11786-1-ap","title":"Proteintech, 11786-1-AP, CCL11\/Eotaxin Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CCL11\/Eotaxin (11786-1-AP) by Proteintech is a Polyclonal antibody targeting CCL11\/Eotaxin in IHC, ELISA applications with reactivity to human samples\n11786-1-AP targets CCL11\/Eotaxin in IHC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: human lung squamous cell carcinoma tissue, human tonsillitis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:800-1:3200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCCL11 also named Eotaxin-1, was initially discovered as an eosinophil-specific chemoattractant. CCL11 plays a central role in both allergic and non-allergic inflammatory reactions by recruiting immune cells such as eosinophils,basophils and Th2 lymphocytes. CCL11 binds to the chemokine receptors CCR2, CCR3 and CCR5, with highest affinity to CCR3. High levels of CCL11 have been described in several chronic inflammatory diseases, such as allergic rhinitis, atopic dermatitis, asthma, gastrointestinal disease and rheumatoid arthritis.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag2398 Product name: Recombinant human Eotaxin protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-97 aa of BC017850 Sequence: MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP Predict reactive species\nFull Name: chemokine (C-C motif) ligand 11\nCalculated Molecular Weight: 97 aa, 11 kDa\nGenBank Accession Number: BC017850\nGene Symbol: CCL11\/Eotaxin\nGene ID (NCBI): 6356\nRRID: AB_10860099\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P51671\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869522120873,"sku":"11786-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-11786-1-ap","provider":"Iright","version":"1.0","type":"link"}