{"product_id":"proteintech-12297-1-ap","title":"Proteintech, 12297-1-AP, Neurotrophin 4 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe Neurotrophin 4 (12297-1-AP) by Proteintech is a Polyclonal antibody targeting Neurotrophin 4 in WB, IF\/ICC, ELISA applications with reactivity to human, mouse, rat samples\n12297-1-AP targets Neurotrophin 4 in WB, IHC, IF\/ICC, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A431 cells, mouse brain tissue,  rat brain tissue,  rat cerebellum tissue,  rat kidney tissue\nPositive IF\/ICC detected in: PC-3 cells, SH-SY5Y cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:3000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nNeurotrophin 4 (NT-4) belongs to the family of neurotrophic factors, and it interacts with the tyrosine kinase B (trkB) receptor. NT-4  has neuroprotective effects following cerebral ischemia. Its role might be similar to brain-derived neurotrophic factor (BDNF) because both interact with trkB. Exercise also improves neural function by increasing neurotrophic factors. NT-4 exists in two forms, either as a dimer (80 kDa) or as a monomer (40-47 kDa) (PMID: 23526925).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag2938 Product name: Recombinant human NTF4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-210 aa of BC012421 Sequence: MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA Predict reactive species\nFull Name: neurotrophin 4\nCalculated Molecular Weight: 210 aa, 22 kDa\nObserved Molecular Weight: 70-80 kDa\nGenBank Accession Number: BC012421\nGene Symbol: Neurotrophin 4\nGene ID (NCBI): 4909\nRRID: AB_10598309\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P34130\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869565898921,"sku":"12297-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-12297-1-ap","provider":"Iright","version":"1.0","type":"link"}