{"product_id":"proteintech-12608-1-ap","title":"Proteintech, 12608-1-AP, USP12 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe USP12 (12608-1-AP) by Proteintech is a Polyclonal antibody targeting USP12 in WB, ELISA applications with reactivity to human, mouse, rat samples\n12608-1-AP targets USP12 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293 cells, mouse kidney tissue,  rat kidney tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nUbiquitin-specific peptidase 12 (USP12) belongs to the ubiquitin-specific protease (USP) family of deubiquitinases that are critical for ubiquitin signaling and protein quality control. USPs function as cysteine proteases to trim or remove ubiquitin conjugates from selected substrates. Deubiquitination is important for ubiquitin signaling-mediated processes, such as regulation of protein levels or activity. Depletion of USP12 suppressed cell growth and clonogenicity and inhibited autophagy(PMID: 30266909 34997217 35898171).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag3309 Product name: Recombinant human USP12 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-370 aa of BC026072 Sequence: MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD Predict reactive species\nFull Name: ubiquitin specific peptidase 12\nCalculated Molecular Weight: 370 aa, 43 kDa\nObserved Molecular Weight: 38 kDa\nGenBank Accession Number: BC026072\nGene Symbol: USP12\nGene ID (NCBI): 219333\nRRID: AB_10641037\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O75317\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869626355881,"sku":"12608-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-12608-1-ap","provider":"Iright","version":"1.0","type":"link"}