{"product_id":"proteintech-12754-1-ap","title":"Proteintech, 12754-1-AP, CDCP1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nCDCP1 Polyclonal Antibody for WB, IHC, ELISA\n12754-1-AP targets CDCP1 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, LNCaP cells,  PC-3 cells,  HUH-6 cells,  HepG2 cells,  HuH-7 cells\nPositive IHC detected in: human skin cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCDCP1, also called CD318, TRASK, and SIMA 135, is a 135-140 kDa transmembrane protein containing three CUB domains within the extracellular region and a hexalysine stretch within the cytoplasmic region. A soluble form with MW 80 kDa (p80) is cleaved at an unidentified site on the N-terminal side. CDCP1 is a novel marker for hematopoietic stem cells. CDCP1 is overexpressed in a variety of malignant tumors including respiratory tumors, digestive system cancers, hematological malignancies, and urogenital cancers. It has been recognized as a promising diagnostic biomarker and a potential target for disrupting cancer progression. (PMID: 12799299; PMID: 19514048; PMID: 33509939; PMID: 35504333)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag3439 Product name: Recombinant human CDCP1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-343 aa of BC021099 Sequence: MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVISKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPTLNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESSE Predict reactive species\nFull Name: CUB domain containing protein 1\nCalculated Molecular Weight: 836 aa, 93 kDa\nObserved Molecular Weight: 72 kDa, 130 kDa\nGenBank Accession Number: BC021099\nGene Symbol: CDCP1\nGene ID (NCBI): 64866\nRRID: AB_2078799\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9H5V8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869452226729,"sku":"12754-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-12754-1-ap","provider":"Iright","version":"1.0","type":"link"}