{"product_id":"proteintech-13047-1-ap","title":"Proteintech, 13047-1-AP, DDX11 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe DDX11 (13047-1-AP) by Proteintech is a Polyclonal antibody targeting DDX11 in WB, ELISA applications with reactivity to human samples\n13047-1-AP targets DDX11 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Jurkat cells, K-562 cells,  L02 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDDX11 (DEAD\/H-box helicase 11), also known as hCHLR1, KRG-2, is a member of the DExD\/H (Asp-Glu-x-Asp\/His)-box helicase family containing DNA helicase with roles in DNA replication and sister chromatid cohesion establishment, and general chromosome architecture (PMID: 33802088). DDX11 encodes an iron-sulfur cluster DNA helicase required for development, mutated, and overexpressed in cancers (PMID: 33879618). DDX11 is also a positive regulator of the RIG-I-mitochondrial antiviral signaling protein (MAVS)-mediated signaling pathways (PMID: 39470258).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag3666 Product name: Recombinant human DDX11 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-345 aa of BC011264 Sequence: MANETQKVGAIHFPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWLRDFEQKKREEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVDRLKAEQARRKQREERLQQLQHRVQLKYAAKRLRQEEEERENLLRLSREMLETGPEAERLEQLESGEEELVLAEYESDEEKKVASRVDEDEDDLEEEHITKIYYCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGK Predict reactive species\nFull Name: DEAD\/H (Asp-Glu-Ala-Asp\/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)\nCalculated Molecular Weight: 970 aa, 108 kDa\nObserved Molecular Weight: 102-108 kDa\nGenBank Accession Number: BC011264\nGene Symbol: DDX11\nGene ID (NCBI): 1663\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q96FC9\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887106740393,"sku":"13047-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-13047-1-ap","provider":"Iright","version":"1.0","type":"link"}