{"product_id":"proteintech-13137-1-ap","title":"Proteintech, 13137-1-AP, MINK1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe MINK1 (13137-1-AP) by Proteintech is a Polyclonal antibody targeting MINK1 in WB, IHC, IP, ELISA applications with reactivity to human, mouse, rat samples\n13137-1-AP targets MINK1 in WB, IHC, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue, rat brain tissue\nPositive IP detected in: mouse brain tissue\nPositive IHC detected in: human lymphoma tissue,  human skeletal muscle tissue,  mouse brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\nImmunohistochemistry (IHC): IHC : 1:20-1:200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nMisshapen\/Nck-interacting kinase (NIK)-related kinase 1 (MINK1), also known as mitogen-activated protein 4 kinase 6, a serine-threonine protein kinase belonging to the sterile 20 kinase superfamily, has been implicated in diverse physiological and pathophysiological processes, including platelet activation and thrombus formation (PMID: 38723371). MINK1 has the potential to modulate the activation of NLRP3 inflammasome, indicating its pivotal role in governing pyroptosis. Overall, MINK1 is known to regulate cell senescence, cell motility and migration (PMID: 36182968). MINK1 expression has been demonstrated in multiple tissues and organs, including nervous tissue, kidneys, cancer tissues, and immune system cells. (PMID: 39727954)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag3795 Product name: Recombinant human MINK1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-304 aa of BC034673 Sequence: MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRIQLKD Predict reactive species\nFull Name: misshapen-like kinase 1 (zebrafish)\nCalculated Molecular Weight: 1332 aa, 150 kDa\nObserved Molecular Weight: 150 kDa\nGenBank Accession Number: BC034673\nGene Symbol: MINK1\nGene ID (NCBI): 50488\nRRID: AB_10644151\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q8N4C8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869416018089,"sku":"13137-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-13137-1-ap","provider":"Iright","version":"1.0","type":"link"}