{"product_id":"proteintech-13263-1-ap","title":"Proteintech, 13263-1-AP, CaMKIV Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CaMKIV (13263-1-AP) by Proteintech is a Polyclonal antibody targeting CaMKIV in WB, IHC, ELISA applications with reactivity to human, mouse, rat samples\n13263-1-AP targets CaMKIV in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: human cerebellum tissue,  mouse thymus tissue\nPositive IHC detected in: human ovary cancer tissue, human brain tissue,  human ovary tumor tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2400\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCaMK4 (Calcium\/calmodulin-dependent protein kinase IV) is a multifunctional serine\/threonine kinase that regulates gene expression by activating transcription factors in a wide range of immune cells including T cells and antigen-presenting cells. The function of CaMK4 is suggested to be abnormal mainly in systemic lupus erythematosus (SLE), which is characterized by autoantibody production, immune complex formation, and immune dysregulation (PMID: 29252071). CaMKIV can translocate between the nucleus and cytoplasm (PMID: 21301225)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag3922 Product name: Recombinant human CAMK4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-302 aa of BC025687 Sequence: MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTG Predict reactive species\nFull Name: calcium\/calmodulin-dependent protein kinase IV\nCalculated Molecular Weight: 473 aa, 52 kDa\nObserved Molecular Weight: 56-65 kDa\nGenBank Accession Number: BC025687\nGene Symbol: CAMK4\nGene ID (NCBI): 814\nRRID: AB_2068381\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q16566\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868977811625,"sku":"13263-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-13263-1-ap","provider":"Iright","version":"1.0","type":"link"}