{"product_id":"proteintech-13665-1-ap","title":"Proteintech, 13665-1-AP, CTNNBL1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CTNNBL1 (13665-1-AP) by Proteintech is a Polyclonal antibody targeting CTNNBL1 in WB, IHC, ELISA applications with reactivity to human, mouse samples\n13665-1-AP targets CTNNBL1 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Jurkat cells,  mouse spleen tissue,  mouse thymus tissue\nPositive IHC detected in: human testis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2400\nImmunohistochemistry (IHC): IHC : 1:20-1:200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCTNNBL1, also named as C20orf33, belongs to the armadillo-containing protein family (PMID: 32484799). CTNNBL1 is a widely expressed nucleoprotein that associates with the pre-mRNA processing factor 19 (Prp19) complex of the spliceosome, interacting with its CDC5L component. CTNNBL1 can maintain the content and integrity of the Prp19 spliceosome complex by regulating the interaction between CWC15 and CDC5L (PMID: 28501461). CTNNBL1 has 4 isoforms with the molecular weights of 36, 43, 62 and 65 kDa, respectively. CTNNBL1 may play an important role in colorectal cancer and regulating AID function (PMID: 28501461, 32484799).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag4578 Product name: Recombinant human CTNNBL1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-308 aa of BC036739 Sequence: DANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLRGQQRTRLLNKFTENDSEKVDRLMELHFKYLGAMQVADKKIEGEKHDMVRRGEIIDNDTEEEFYLRRLDAGLFVLQHICYIMAEICNANVPQIRQRVHQILNMRGSSIKIVRHIIKEYAENIGDGRSPEFRENEQKRILGLLENF Predict reactive species\nFull Name: catenin, beta like 1\nCalculated Molecular Weight: 563 aa, 65 kDa\nObserved Molecular Weight: 65 kDa\nGenBank Accession Number: BC036739\nGene Symbol: CTNNBL1\nGene ID (NCBI): 56259\nRRID: AB_2086245\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q8WYA6\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869528772777,"sku":"13665-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-13665-1-ap","provider":"Iright","version":"1.0","type":"link"}