{"product_id":"proteintech-14849-1-ap","title":"Proteintech, 14849-1-AP, KLHL14-Specific Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe KLHL14-Specific (14849-1-AP) by Proteintech is a Polyclonal antibody targeting KLHL14-Specific in WB, IHC, IF\/ICC, ELISA applications with reactivity to human, mouse, rat samples\n14849-1-AP targets KLHL14-Specific in WB, IHC, IF\/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, mouse heart tissue,  mouse testis tissue,  mouse lung tissue,  mouse liver tissue,  SH-SY5Y cells,  mouse brain tissue,  mouse ovary tissue,  HepG2 cells,  rat brain tissue\nPositive IHC detected in: human heart tissue,  human cervical cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: HepG2 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:20-1:200\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nKLHL14, a member of the Kelch-like gene family, has six Kelch domains and is localized to the endoplasmic reticulum. KLHL14, a novel tumor suppressor, is a subunit of a ubiquitin ligase that associates with the endoplasmic reticulum-associated protein degradation (ERAD) machinery, regulating of B cell receptor-dependent NF-κB signaling (PMID: 32127472). KLHL14 has two isoforms of 70kDa and 43kDa.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: kelch-like 14 (Drosophila)\nCalculated Molecular Weight: 70 kDa\nObserved Molecular Weight: 39-45 kDa\nGenBank Accession Number: NM_020805\nGene Symbol: KLHL14\nGene ID (NCBI): 57565\nRRID: AB_2131171\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9P2G3\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869701623977,"sku":"14849-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-14849-1-ap","provider":"Iright","version":"1.0","type":"link"}