{"product_id":"proteintech-15065-1-ap","title":"Proteintech, 15065-1-AP, ANAPC11 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ANAPC11 (15065-1-AP) by Proteintech is a Polyclonal antibody targeting ANAPC11 in WB, ELISA applications with reactivity to human, mouse, rat samples\n15065-1-AP targets ANAPC11 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse testis tissue, rat testis tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nAnaphase-promoting complex subunit 11 (ANAPC11) is a core catalytic subunit of the anaphase-promoting complex\/cyclosome (APC\/C). ANAPC11 is involved in the ubiquitination and degradation of key cell cycle regulators, including cyclin B and securin, facilitating the transition from metaphase to anaphase during cell division (PMID: 11739784; 18485873). ANAPC11 also mediates the ubiquitination and degradation of the Forkhead transcription factor FOXO3, promoting cell proliferation and lymph node metastasis in urothelial bladder cancer (PMID: 37573356).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag7069 Product name: Recombinant human ANAPC11 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-196 aa of BC000607 Sequence: MKVKIKCWNGVATWLWVANDENCGICRMAFNGCCPDCPLHGESISRCLGWCPQPVPVLGGRAHPQVPINTASPTPGQHTGSLMSREESSRSPDPTPPALDQETSSLLRCTSPWCLDHSCDLFGITDQVSADGPRACRQGARRRLPAGVGPVLPLLPHALHPQVAARTAGAAALPHVPPGMEVQGVRPDLALAGGAS Predict reactive species\nFull Name: anaphase promoting complex subunit 11\nCalculated Molecular Weight: 21 kDa, 10 kDa\nObserved Molecular Weight: 21 kDa\nGenBank Accession Number: BC000607\nGene Symbol: APC11\nGene ID (NCBI): 51529\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9NYG5\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869809692841,"sku":"15065-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-15065-1-ap","provider":"Iright","version":"1.0","type":"link"}