{"product_id":"proteintech-15152-1-ap","title":"Proteintech, 15152-1-AP, Prokineticin 1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe Prokineticin 1 (15152-1-AP) by Proteintech is a Polyclonal antibody targeting Prokineticin 1 in IHC, IF\/ICC, ELISA applications with reactivity to human, mouse, rat samples\n15152-1-AP targets Prokineticin 1 in IHC, IF\/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: human colon cancer tissue, mouse kidney tissue,  mouse liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: NIH\/3T3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nProkineticin 1 (PROK1) is also named as EG-VEGF and Mambakine, belongs to the to the AVIT (prokineticin) family. Prokineticin signaling comprises two secreted proteins (Prok-1 and Prok-2) and two cognate G-protein coupled receptors (PK-R1 and PK-R2) that are widely expressed in different tissues and of great versatility. Prokineticins were shown to promote angiogenesis in steroidgenic glands, heart and reproductive organs (PMID:18440852). PROK1 has been described as a secretory protein with pleiotropic functions and as a novel tissue-specific angiogenic factor (PMID:32355954). EG-VEGF\/PK-1, described as selective angiogenic mitogen, is widely expressed in different tissues including steroidogenic endocrine glands (PMID:16320832). A lot of data suggests EG-VEGF to be restricted to endocrine glands and to some endocrine-dependent organs (PMID:28386275).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag5098 Product name: Recombinant human PROK1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-105 aa of BC025399 Sequence: MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEECHPGSHKIPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF Predict reactive species\nFull Name: prokineticin 1\nCalculated Molecular Weight: 12 kDa\nGenBank Accession Number: BC025399\nGene Symbol: Prokineticin 1\nGene ID (NCBI): 84432\nRRID: AB_3669199\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P58294\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887774126249,"sku":"15152-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-15152-1-ap","provider":"Iright","version":"1.0","type":"link"}