{"product_id":"proteintech-15935-1-ap","title":"Proteintech, 15935-1-AP, ABCD4 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ABCD4 (15935-1-AP) by Proteintech is a Polyclonal antibody targeting ABCD4 in WB, ELISA applications with reactivity to human, mouse samples\n15935-1-AP targets ABCD4 in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, HepG2 cells,  Jurkat cells,  mouse liver tissue,  mouse skeletal muscle tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nABCD4, also known as P70R, PMP69, and PXMP1L, belongs to the ATP-binding cassette (ABC) transporter superfamily. ABCD4 Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner (PMID: 22922874, 33845046, 28572511). ABCD4 is involved in peroxisomal import of fatty acids and\/or fatty acyl-CoAs in the organelle. Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism, which is related to methylmalonic aciduria and homocystinuria type cblJ (MAHCJ).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nCited Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag8783 Product name: Recombinant human ABCD4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 335-606 aa of BC012815 Sequence: SDVAGYTHRIGQLRETLLDMSLKSQDCEILGESKWGLDTPPGWPAAEPADTAFLLERVSISAPSSDKPLIKDLSLKISEGQSLLITGNTGTGKTSLLRVLGGLWTSTRGSVQMLTDFGPHGVLFLPQKPFFTDGTLREQVIYPLKEVYPDSGSADDERILRFLELAGLSNLVARTEGLDQQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEVESELYRIGQQLGMTFISVGHRQSLEKFHSLVLKLCGGGRWELMRIKVE Predict reactive species\nFull Name: ATP-binding cassette, sub-family D (ALD), member 4\nCalculated Molecular Weight: 606 aa, 69 kDa\nObserved Molecular Weight: 70 kDa\nGenBank Accession Number: BC012815\nGene Symbol: ABCD4\nGene ID (NCBI): 5826\nRRID: AB_3085475\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O14678\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869629927593,"sku":"15935-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-15935-1-ap","provider":"Iright","version":"1.0","type":"link"}