{"product_id":"proteintech-15949-1-ap","title":"Proteintech, 15949-1-AP, DYNC2LI1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe DYNC2LI1 (15949-1-AP) by Proteintech is a Polyclonal antibody targeting DYNC2LI1 in WB, ELISA applications with reactivity to human, mouse samples\n15949-1-AP targets DYNC2LI1 in WB, IF, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293T cells, L02 cells,  mouse brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDYNC2LI1 (D2LIC, LIC3) is a member of cytoplasmic dynein 2 complex that is required for retrograde transport. It is ubiquitously expressed with high expression levels in brain, kidney, lung and testes. In mammalian cells, DYNC2LI1 is localized to centrosomal region Mutations in DYNC2LI1 disrupt cilia function and cause various skeletal ciliopathies. There're some isoforms with MW 40 kDa, 38 kDa, 22 kDa and 16 kDa.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag8584 Product name: Recombinant human DYNC2LI1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-352 aa of BC006969 Sequence: MPSETLWEIAKAEVEKRGINGSEGDGAEIAEKFVFFIGSKNGGKTTIILRCLDRDEPPKPTLALEYTYGRRAKGHNTPKDIAHFWELGGGTSLLDLISIPITGDTLRTFSLVLVLDLSKPNDLWPTMENLLQATKSHVDKVIMKLGKTNAKAVSEMRQKIWNNMPKDHPQDHELIDPFPVPLVIIGSKYDVFQDFESEKRKVICKTLRFVAHYYGASLMFTSKSEALLLKIRGVINQLAFGIDKSKSICVDQNKPLFITAGLDSFGQIGSPPVPENDIGKLHAHSPMELWKKVYEKLFPPKSINTLKDIKDPARDPQYAENEVDEMRIQKDLELEQYKRSSSKSWKQIELDS Predict reactive species\nFull Name: dynein, cytoplasmic 2, light intermediate chain 1\nCalculated Molecular Weight: 352 aa, 40 kDa\nObserved Molecular Weight: 37-40 kDa, 22 kDa\nGenBank Accession Number: BC006969\nGene Symbol: DYNC2LI1\nGene ID (NCBI): 51626\nRRID: AB_2093643\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q8TCX1\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868979450025,"sku":"15949-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-15949-1-ap","provider":"Iright","version":"1.0","type":"link"}