{"product_id":"proteintech-16278-1-ap","title":"Proteintech, 16278-1-AP, CHMP6 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CHMP6 (16278-1-AP) by Proteintech is a Polyclonal antibody targeting CHMP6 in WB, IHC, IP, ELISA applications with reactivity to human, mouse, rat samples\n16278-1-AP targets CHMP6 in WB, IHC, IF, IP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse testis tissue,  A375 cells,  A431 cells,  Jurkat cells,  U-937 cells\nPositive IP detected in: mouse testis tissue\nPositive IHC detected in: human stomach tissue, human colon  cancerNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCHMP6 (charged multivesicular body protein 6) is a protein that plays a significant role in the formation of multivesicular bodies (MVBs) within cells. It is a component of the endosomal sorting complex required for transport III (ESCRT-III), which is involved in the sorting and transport of proteins within the cell. CHMP6 has been identified as a novel prognostic biomarker in bladder cancer, where it enhances cell survival and migration by regulating the cell cycle. (PMID: 40630215)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse, canine\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag9357 Product name: Recombinant human CHMP6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-201 aa of BC010108 Sequence: MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKIPENVPVKARPRQAELVAAS Predict reactive species\nFull Name: chromatin modifying protein 6\nCalculated Molecular Weight: 201 aa, 23 kDa\nObserved Molecular Weight: 28-30 kDa\nGenBank Accession Number: BC010108\nGene Symbol: CHMP6\nGene ID (NCBI): 79643\nRRID: AB_2079498\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q96FZ7\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868963852457,"sku":"16278-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-16278-1-ap","provider":"Iright","version":"1.0","type":"link"}