{"product_id":"proteintech-16739-1-ap","title":"Proteintech, 16739-1-AP, TASP1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe TASP1 (16739-1-AP) by Proteintech is a Polyclonal antibody targeting TASP1 in WB, IHC, IF\/ICC, ELISA applications with reactivity to human, mouse, rat samples\n16739-1-AP targets TASP1 in WB, IHC, IF\/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293 cells,  HeLa cells\nPositive IHC detected in: human ovary tissue,  human kidney tissue,  human liver tissue,  human lung tissue,  human testis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:20-1:200\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:20-1:200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThreonine aspartase 1 (TASP1), a particularly conserved protease that cleaves mixed lineage leukemia 1 (MLL), regulates the expression of homeotic genes and is involved in the occurrence of cancer. TASP1 drives cell cycle progression and coordinates cell proliferation and apoptosis (PMID: 33767369). Aberrant expression of TASP1 has been found in numerous liquid and solid malignancies, including leukaemia, breast cancer, lung cancer, head and neck cancer, brain cancer, colon cancer, glioblastoma and melanoma. TASP1 plays a key role in cancer cell proliferation and apoptosis and can inhibit tumor growth after knockout (PMID: 32071545, 34012990).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag9918 Product name: Recombinant human TASP1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-420 aa of BC025266 Sequence: MTMEKGMSSGEGLPSRSSQVSAGKITAKELETKQSYKEKRGGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVTAALVELEDSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPNIMTTRFSLAAFKRNKRKLELAERVDTDFMQLKKRRQSSEKENDSGTLDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAHNPYSTAVSTSGCGEHLVRTILARECSHALQAEDAHQALLETMQNKFISSPFLASEDGVLGGVIVLRSCRCSAEPDSSQNKQTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN Predict reactive species\nFull Name: taspase, threonine aspartase, 1\nCalculated Molecular Weight: 420 aa, 44 kDa\nObserved Molecular Weight: 50 kDa\nGenBank Accession Number: BC025266\nGene Symbol: TASP1\nGene ID (NCBI): 55617\nRRID: AB_2201218\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9H6P5\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869611446441,"sku":"16739-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-16739-1-ap","provider":"Iright","version":"1.0","type":"link"}