{"product_id":"proteintech-17139-1-ap","title":"Proteintech, 17139-1-AP, FBXL13 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe FBXL13 (17139-1-AP) by Proteintech is a Polyclonal antibody targeting FBXL13 in IHC, ELISA applications with reactivity to human samples\n17139-1-AP targets FBXL13 in IHC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: human liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nFBXL13, a binding determinant of SCF (SKP1-CUL1-F-box)-family E3 ubiquitin ligases, is enriched at centrosomes and interacts with the centrosomal proteins Centrin-2, Centrin-3, CEP152 and CEP192. Induced FBXL13 expression downregulates centrosomal γ-tubulin and disrupts centrosomal microtubule arrays. FBXL13 is a novel regulator of microtubule nucleation activity and participate in promoting cell motility with potential tumour-promoting implications (PMID: 29348145).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag10903 Product name: Recombinant human FBXL13 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 358-707 aa of BC031285 Sequence: NDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMSSKVQQQEYNTNGPPRWFGYDREGNPVTELDNITSSKGALELTVKKSTYSSEDQAA Predict reactive species\nFull Name: F-box and leucine-rich repeat protein 13\nCalculated Molecular Weight: 707 aa, 81 kDa\nGenBank Accession Number: BC031285\nGene Symbol: FBXL13\nGene ID (NCBI): 222235\nRRID: AB_2103869\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q8NEE6\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887635845289,"sku":"17139-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-17139-1-ap","provider":"Iright","version":"1.0","type":"link"}