{"product_id":"proteintech-17197-1-ap","title":"Proteintech, 17197-1-AP, WDFY2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe WDFY2 (17197-1-AP) by Proteintech is a Polyclonal antibody targeting WDFY2 in WB, IF\/ICC, ELISA applications with reactivity to human, mouse samples\n17197-1-AP targets WDFY2 in WB, IF\/ICC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: L-929 cells, 3T3-L1 cells\nPositive IF\/ICC detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nWDFY2, also named Prof, is a protein that contains WD repeats and an FYVE domain. WDFY2 regulates the membrane-bound matrix metalloproteinase MT1-MMP (MMP14)  efflux by controlling endosome sorting. WDFY2 may act as a tumor suppressor by limiting VAMP3-dependent recycling to inhibit matrix metalloproteinase secretion and cell invasion (PMID: 31253801). WDFY2 in the cell nucleus directly participates in homologous recombination-mediated DNA repair (PMID: 41196680).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag10415 Product name: Recombinant human WDFY2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 72-400 aa of BC014004 Sequence: SCMSFNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMILFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATFHDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS Predict reactive species\nFull Name: WD repeat and FYVE domain containing 2\nCalculated Molecular Weight: 400 aa, 45 kDa\nObserved Molecular Weight: 45 kDa\nGenBank Accession Number: BC014004\nGene Symbol: WDFY2\nGene ID (NCBI): 115825\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q96P53\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887921909929,"sku":"17197-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-17197-1-ap","provider":"Iright","version":"1.0","type":"link"}