{"product_id":"proteintech-18816-1-ap","title":"Proteintech, 18816-1-AP, CAMSAP1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CAMSAP1 (18816-1-AP) by Proteintech is a Polyclonal antibody targeting CAMSAP1 in WB, ELISA applications with reactivity to human, mouse samples\n18816-1-AP targets CAMSAP1 in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: SH-SY5Y cells, mouse brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCAMSAP1, or Calmodulin-regulated spectrin-associated protein 1, is a protein that plays a crucial role in the formation and maintenance of the minus end of non-centrosomal microtubules, which are essential for proper neuronal function and development. Research has shown that CAMSAP1 is vital for neuronal polarization, migration, and cortical lamination. CAMSAP1 has also been implicated in cancer prognosis. A study found that CAMSAP1 mutation can activate anti-tumor immunity, mediate tumor cell apoptosis, inhibit epithelial-mesenchymal transition (EMT), improve prognosis, and improve platinum drug sensitivity in small-cell lung cancer patients treated with platinum-based chemotherapy, suggesting that CAMSAP1 mutation may be a potential biomarker indicating platinum drug sensitivity and patient prognosis. The CAMSAP1 of the calculated MW is around 170 kDa, and the observed MW is 245 kDa (PMID: 32839317).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: calmodulin regulated spectrin-associated protein 1\nCalculated Molecular Weight: 179 kDa\nObserved Molecular Weight: 245 kDa\nGenBank Accession Number: BC144082\nGene Symbol: CAMSAP1\nGene ID (NCBI): 157922\nRRID: AB_3669303\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q5T5Y3\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46885791629481,"sku":"18816-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-18816-1-ap","provider":"Iright","version":"1.0","type":"link"}