{"product_id":"proteintech-19962-1-ap","title":"Proteintech, 19962-1-AP, ITPR1-specific Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ITPR1-specific (19962-1-AP) by Proteintech is a Polyclonal antibody targeting ITPR1-specific in WB, IHC, IF-Fro, FC (Intra), IP, ELISA applications with reactivity to human, mouse, rat samples\n19962-1-AP targets ITPR1-specific in WB, IHC, IF-Fro, FC (Intra), IP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HepG2 cells, mouse brain tissue,  mouse liver tissue,  L02 cells,  rat brain tissue\nPositive IP detected in: mouse brain tissue\nPositive IHC detected in: human brain tissue, human testis tissue,  mouse brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF-Fro detected in: mouse brain tissue\nPositive FC (Intra) detected in: HepG2 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:8000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)-FRO: IF-FRO : 1:500-1:2000\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.20 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nITPR1, also named as INSP3R1 and IP3R, belongs to the InsP3 receptor family. It is a receptor for inositol 1,4,5-trisphosphate which is a second messenger that mediates the release of intracellular calcium. Defects in ITPR1 are the cause of spinocerebellar ataxia type 15 (SCA15). The antibody has no cross reaction with ITPR2 and ITPR3.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse, rat, chicken, bovine, sheep, duck\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: inositol 1,4,5-triphosphate receptor, type 1\nCalculated Molecular Weight: 314 kDa\nObserved Molecular Weight: 290-300 kDa\nGenBank Accession Number: NM_001099952\nGene Symbol: ITPR1\nGene ID (NCBI): 3708\nRRID: AB_10638786\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q14643\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868852637865,"sku":"19962-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-19962-1-ap","provider":"Iright","version":"1.0","type":"link"}