{"product_id":"proteintech-19988-1-ap","title":"Proteintech, 19988-1-AP, LDHB-Specific Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe LDHB-Specific (19988-1-AP) by Proteintech is a Polyclonal antibody targeting LDHB-Specific in WB, IHC, IF\/ICC, ELISA applications with reactivity to human, mouse, rat samples\n19988-1-AP targets LDHB-Specific in WB, IHC, IF\/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: DU 145 cells, HeLa cells,  HEK-293T cells,  Jurkat cells,  PC-3 cells,  mouse heart tissue,  rat heart tissue\nPositive IHC detected in: human ovary cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\nImmunohistochemistry (IHC): IHC : 1:300-1:1200\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nLDHB, also named as NY-REN-46 and LDH-H, belongs to the LDH\/MDH superfamily and LDH family. LDHB catalyzes the reaction: (S)-lactate + NAD+ = pyruvate + NADH. It is an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. It is glycolytic enzymes and it is positively regulated by mTOR.Defects in LDHB are a cause of hereditary LDHB deficiency. The antibody is specific to LDHB and has no cross reaction with LDHA and LDHC.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: lactate dehydrogenase B\nCalculated Molecular Weight: 37 kDa\nObserved Molecular Weight: 35 kDa\nGenBank Accession Number: NM_002300\nGene Symbol: LDHB\nGene ID (NCBI): 3945\nRRID: AB_10638780\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P07195\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868969291945,"sku":"19988-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-19988-1-ap","provider":"Iright","version":"1.0","type":"link"}