{"product_id":"proteintech-20297-1-ap","title":"Proteintech, 20297-1-AP, P2RY2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe P2RY2 (20297-1-AP) by Proteintech is a Polyclonal antibody targeting P2RY2 in WB, IHC, ELISA applications with reactivity to human samples\n20297-1-AP targets P2RY2 in WB, IHC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HL-60 cells, MCF-7 cells,  PC-3 cells,  MDA-MB-231 cells\nPositive IHC detected in: human brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nP2RY2, also named P2RU1, P2U1, and P2Y2, belongs to the G-protein coupled receptor 1 family. It is a receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Extracellular ATP then acts on purinergic receptors, including P2RY2, to activate proline-rich tyrosine kinase 2 (Pyk2) kinase and transient plasma membrane depolarization.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag14107 Product name: Recombinant human P2RY2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 268-377 aa of BC012104 Sequence: YYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQSLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL Predict reactive species\nFull Name: purinergic receptor P2Y, G-protein coupled, 2\nCalculated Molecular Weight: 377 aa, 42 kDa\nObserved Molecular Weight: 45 kDa\nGenBank Accession Number: BC012104\nGene Symbol: P2RY2\nGene ID (NCBI): 5029\nRRID: AB_3669332\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P41231\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887748665513,"sku":"20297-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-20297-1-ap","provider":"Iright","version":"1.0","type":"link"}