{"product_id":"proteintech-20548-1-ap","title":"Proteintech, 20548-1-AP, ERCC6\/CSB Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ERCC6\/CSB (20548-1-AP) by Proteintech is a Polyclonal antibody targeting ERCC6\/CSB in WB, ELISA applications with reactivity to human, mouse, rat samples\n20548-1-AP targets ERCC6\/CSB in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:200-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nERCC6, also named as CSB, belongs to the SNF2\/RAD54 helicase family. It is involved in the preferential repair of active genes. It is presumed DNA or RNA unwinding function. ERCC6 corrects the UV survival and RNA synthesis after UV exposure of Cockayne syndrome complementation group B. Defects in ERCC6 are the cause of Cockayne syndrome type B (CSB) , cerebro-oculo-facio-skeletal syndrome type 1 (COFS1), De Sanctis-Cacchione syndrome (DSC), and UV-sensitive syndrome (UVS). Genetic variation in ERCC6 is associated with susceptibility to age-related macular degeneration type 5 (ARMD5). The antibody is specific to ERCC6.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: excision repair cross-complementing rodent repair deficiency, complementation group 6\nCalculated Molecular Weight: 168 kDa\nObserved Molecular Weight: 150 kDa\nGenBank Accession Number: NM_000124\nGene Symbol: ERCC6\/CSB\nGene ID (NCBI): 2074\nRRID: AB_10732961\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q03468\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887627161769,"sku":"20548-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-20548-1-ap","provider":"Iright","version":"1.0","type":"link"}